Focus on Neurochemistry ResearchThe brain is an enormously dynamic organ. Even when we sleep connections are made, signals sent and messages delivered. One of the key ways that the brain operates is via chemical stimuli which permits different parts of the brain to communicate between themselves and with the rest of the body. Determining what these chemicals, proteins and molecules are is an important way to not only discover how the brain works, but provide novel targets that may be useful in the treatment of disease, for instance in dealing with memory loss in dementia. This new book brings together international research in a broad range of topics, including molecular and cellular neurochemistry, neuropharmacology and genetic aspects of CNS function, neuroimmunology, metabolism, as well as the neurochemistry of neurological and psychiatric disorders of the CNS. |
Contents
1 | |
Ethanol Induced Adaptive Changes in Structure and Function of NMDA Receptors | 61 |
Benzodiazepines as Modulators of Neurotransmission | 101 |
Expression of Cytokines and Costimulatory Molecules by Activated Human Microglia | 117 |
Prevention of Ischemic Neuron Death by a Saffrons Carotenoid Pigment Crocin and its Mechanism of Action | 139 |
Neurochemistry of Epileptic Seizures The Role of fActin Intercellular Glutamate and Glutamate Ionotropic Receptors Location | 157 |
Uptake of Amino Acid Neurotransmitters into Synaptic Vesicles A Target for 5aminolevulinic acid | 197 |
Potential Mechanisms of Methylmercury MeHgInduced Neurotoxicity The Role of Glutamate and Reactive Oxygen Species ROS | 213 |
Purine Nucleoside Mediated Protection of Primary Cerebellar Granule Cells after Hypoxic Insult | 229 |
Index | 247 |
Common terms and phrases
acamprosate action activity adenosine alcohol amino acid AMPA antioxidant Aschner astrocytes axons benzodiazepines Biol Brain Res Ca2+ calcineurin calcium cell death cellular ceramide cerebellar granule cells cerebral channels chemokines chronic ethanol crocin cytokines dendritic spines effect energy metabolism ethanol ethanol withdrawal excitatory expression extracellular glutamate extrasynaptic Figure function GABA GABAA receptors GABAergic glia glial cells glucose glutamate receptors glutamate transporter glutamatergic glycine glycogen granule cells guanosine Hertz hippocampal hippocampal neurons increase induced infection inhibition inhibitor inosine interactions jasplakinolide K+ concentration latrunculin-A levels mechanisms mediated MeHg membrane methylmercury microglia modulation molecule neurite Neurochem neurons Neurosci neurotoxicity neurotransmitter NMDAR NMDAR antagonists NR2B subunit nSMase oxidative metabolism PC-12 cells perfused Pharmacol phosphorylation picrotoxin postsynaptic potential primary cultures purine nucleosides pyruvate rat brain rat cortical regulation release role seizures Sierra-Paredes signaling stimulation studies synaptic vesicles transmitter tuberculosis vitro vivo
Popular passages
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