Focus on Neurochemistry Research

Front Cover
Nova Publishers, 2005 - Medical - 255 pages
The brain is an enormously dynamic organ. Even when we sleep connections are made, signals sent and messages delivered. One of the key ways that the brain operates is via chemical stimuli which permits different parts of the brain to communicate between themselves and with the rest of the body. Determining what these chemicals, proteins and molecules are is an important way to not only discover how the brain works, but provide novel targets that may be useful in the treatment of disease, for instance in dealing with memory loss in dementia. This new book brings together international research in a broad range of topics, including molecular and cellular neurochemistry, neuropharmacology and genetic aspects of CNS function, neuroimmunology, metabolism, as well as the neurochemistry of neurological and psychiatric disorders of the CNS.

From inside the book

Contents

The NeuronalGlial Brain Fine Structure Ion Homeostasis and Glucose Metabolism
1
Ethanol Induced Adaptive Changes in Structure and Function of NMDA Receptors
61
Benzodiazepines as Modulators of Neurotransmission
101
Expression of Cytokines and Costimulatory Molecules by Activated Human Microglia
117
Prevention of Ischemic Neuron Death by a Saffrons Carotenoid Pigment Crocin and its Mechanism of Action
139
Neurochemistry of Epileptic Seizures The Role of fActin Intercellular Glutamate and Glutamate Ionotropic Receptors Location
157
Uptake of Amino Acid Neurotransmitters into Synaptic Vesicles A Target for 5aminolevulinic acid
197
Potential Mechanisms of Methylmercury MeHgInduced Neurotoxicity The Role of Glutamate and Reactive Oxygen Species ROS
213
Purine Nucleoside Mediated Protection of Primary Cerebellar Granule Cells after Hypoxic Insult
229
Index
247
Copyright

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Page 94 - Mihic, SJ, Ye, Q., Wick, MJ, Koltchine, VV, Krasowski, MD, Finn, SE, Mascia, MP, Valenzuela, CF, Hanson, KK, Greenblatt, EP, Harris, RA, and Harrison, NL (1997).
Page 93 - Kuhse, J. and Betz, H. (1998) Evidence for a tetrameric structure of recombinant NMDA receptors. J. Neurosci., 18: 2954-2961.
Page 94 - Seeburg, PH, 1994. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron, 12, 529-540.
Page 95 - Hamon, M. (1995). Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism.
Page 243 - B. (1979) Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells. J. Neurochem.
Page 112 - SG, 1994. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci, 14, 5559-5569.
Page 188 - SF and Westbrook, GL (1999) Interactions of calmodulin and alpha-actinin with the NR1 subunit modulate Ca2+dependent inactivation of NMDA receptors.

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