Selection in Natural PopulationsIn 1974, Richard Lewontin published The Genetic Basis of Evolutionary Change, focusing enormous attention on protein variation as both a model of underlying genetic variation and a level of selection itself. In the twenty years since, scientific research has been shifted by the power of molecular biological techniques to explore the nature of variation directly at the DNA and gene levels. The "protein chapter" is coming to a close. In this book, Jeff Mitton explains the questions that geneticists hoped to answer by studying protein variation. He reviews the extensive literature on protein variation, describes the successes and failures of the research program, and evaluates the results of a rich and controversial body of research. The laboratory and field studies using protein polymorphisms revealed dynamic interactions among genotypes, fitness differentials, and fluctuating environmental conditions, and inadvertently wedded the fields of physiological ecology and population biology. Mitton's book is a useful analysis for all scientists interested in the genetic structure and evolution of populations. |
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... Electrophoretic Profiles Classes of Proteins 60 Reliably Polymorphic Loci 60 Quaternary structure Subunity size 61 58 58 61 62 The Kluge - Kerfoot Phenomenon Discordant Patterns of Geographic Variation 68 Summary 71 6 The Axis of ...
... Electrophoretic Profiles Classes of Proteins 60 Reliably Polymorphic Loci 60 Quaternary structure Subunity size 61 58 58 61 62 The Kluge - Kerfoot Phenomenon Discordant Patterns of Geographic Variation 68 Summary 71 6 The Axis of ...
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Contents
Natural Selection Fitness Determination and Molecular Variation | 3 |
Classes of Abundant Genetic Variation | 14 |
Selection on mitochondrial genome size | 20 |
The Randomness of a Sample of Proteins | 26 |
The Impact of a Single Gene | 41 |
Patterns of Variation Among Loci | 58 |
Discordant Patterns of Geographic Variation | 68 |
Empirical Data | 87 |
Female Choice and Male Fitness | 127 |
Patterns among Species | 144 |
Surveys of Natural Populations | 150 |
Summary | 156 |
Comments on Natural Selection | 167 |
Average Heterozygosity and Genetic Distance Among | 175 |
Heterozygosity and Maximum Lifetime Fecundity | 192 |
233 | |
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Common terms and phrases
3000 Drosophila allelic frequencies allozyme allozyme heterozygosity amino acid animals average heterozygosity Avise axis Ayala biochemical biologists blue mussel chapter chromosomes coefficients Colias common components of fitness correlation dehydrogenase developmental stability differences differentiation Drosophila melanogaster eggs electrophoretic environmental heterogeneity environments enzyme kinetics enzyme loci equilibrium erozygosity estimated evolution evolutionary favored fecundity female choice figure fish fluctuating asymmetry Fundulus heteroclitus gene flow genetic distance genetic variation genome genus geographic range growth rate Hamrick hemoglobin heterozy heterozygous highly heterozygous homozygotes homozygous increased with heterozygosity individual heterozygosity killifish kinetic Koehn levels of genetic linkage disequilibrium markers mating success measured metabolic Mitton molecular morphological mtDNA multilocus natural populations natural selection Nevo offspring overdominance oxygen consumption pattern Peromyscus physiological pine plants polymorphic loci polymorphisms predictions produced protein protein polymorphisms relationship revealed salinity sample sexual selection species studies substrate temperature tion truncation selection vari variability variance viability Zouros zygotic
Popular passages
Page 209 - Scott. 1984. Multiple-locus heterozygosity and the physiological energetics of growth in the coot clam, Mulinia lateralis, from a natural population.
Page 226 - Scheltema, RS (1977) Dispersal of marine invertebrate organisms: Paleobiogeographic and biostratigraphic implications. Pp. 73-108. In: Kauffman, EG and JE Hazel (eds.). Concepts and Methods of Biostratigraphy.
Page 209 - WJ. Diehl. 1990. Interrelationships of heterozygosity, growth rate and heterozygote deficiencies in the coot clam, Mulinia lateralis. Genetics 124:687-699.
Page 213 - Jeffreys, AJ, Royle, NJ, Wilson, V., and Wong, Z. (1988) Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA.
Page 225 - Rogers, S., Wells, R. and Rechsteiner, M. (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.
Page 203 - Brown, JL 1997. A theory of mate choice based on heterozygosity. Behav. Ecol.
Page 206 - Diamond, SA, MC Newman, M. Mulvey, PM Dixon and D. Martinson, 1989. Allozyme genotype and time to death of mosquitofish, Gambusia affinis (Baird and Girard), during acute exposure to inorganic mercury. Environ. Toxicol. Chem.
Page 213 - minisatellite" regions in human DNA. Nature 314:67-73. Jeffreys, AJ, V. Wilson, and SL Thein. 1985b. Individual-specific "fingerprints
Page 215 - Bivalve species duration, areal extent and population size in a Cretaceous sea.