The Hippocampus BookPer Andersen, Richard Morris, David Amaral, Tim Bliss, John O'Keefe The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf. |
Contents
| 3 | |
| 9 | |
Chapter 3 Hippocampal Neuroanatomy | 37 |
Chapter 4 Morphological Development of the Hippocampus | 115 |
Chapter 5 Structural and Functional Properties of Hippocampal Neurons | 133 |
Chapter 6 Synaptic Function | 203 |
Neurotransmitter Exocytosis and Glutamatergic GABAergic and Cholinergic Transmission | 243 |
Chapter 8 Local Circuits | 297 |
Chapter 11 Hippocampal Neurophysiology in the Behaving Animal | 475 |
Chapter 12 Functional Role of the Human Hippocampus | 549 |
Chapter 13 Theories of Hippocampal Function | 581 |
Chapter 14 Computational Models of the Spatial and Mnemonic Functions of the Hippocampus | 715 |
Chapter 15 Stress and the Hippocampus | 751 |
Chapter 16 Hippocampus and Human Disease | 769 |
References | 803 |
| 813 | |
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The Hippocampus Book Per Andersen,Richard Morris,David Amaral,Tim Bliss,John O'Keefe Limited preview - 2006 |
Common terms and phrases
Acad Sci USA action potentials activity adult afferent AMPA animals area CA1 axons basket cells Brain Res CA1 neurons CA1 pyramidal cells CA1 pyramidal neurons CaMKII cell layer Comp Neurol cortical dendritic spines dentate gyrus depolarization depotentiation distal entorhinal cortex EPSPs excitatory expression firing function GABA GABAA receptors GABAergic gene GluR1 GluR2 glutamate receptors granule cells hippocampal formation hippocampal neurons hippocampal slices increase induction of LTP inhibition inhibitory innervate input interneurons intracellular kainate receptors kinase knockout learning located long-term potentiation mechanisms mediated membrane memory metabotropic mGluRs mice molecular layer monkey mossy fiber Natl Acad Sci neurogenesis Neurophysiol Neurosci NMDA receptor pathway perforant path Physiol place cells place fields pocampal postsynaptic presubiculum presynaptic Proc Natl Acad projection protein pyramidal neurons rat hippocampus region release response role septal soma spatial spike stimulation studies subiculum synaptic plasticity synaptic transmission target terminals tetanus theta tion types vesicles vitro vivo