Inflammatory Bowel Disease: From Bench to Bedside

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Stephan R. Targan, Fergus Shanahan, Loren C. Karp
Springer Science & Business Media, May 16, 2007 - Medical - 904 pages
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Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

 

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Contents

The changing faces of Crohns disease and ulcerative colitis
5
Surgery for Crohns disease
19
Genetics of inflammatory bowel disease
64
a state of controlled inflammation
101
The lymphocyteepithelialbacterial interface
121
The mucosal inflammatory response Cytokines and chemokines
147
Role of the microcirculation in chronic gut inflammation
177
Remission relapse intestinal healing and repair
197
optimizing current medical therapy
495
Multisite therapeutic modalities for inflammatory bowel diseases mechanisms of action
522
Targeted therapies for inflammatory bowel disease
554
Nutrition in inflammatory bowel disease
596
Surgical management of ulcerative colitis
630
clinical characteristics and management
654
Medical therapy for Crohns disease
676
Robin S McLeod
683

Antibodies in the exploration of inflammatory bowel disease pathogenesis
214
Systemic consequences of intestinal inflammation
235
Understanding symptoms and signs in inflammatory bowel disease
266
Clinical course and complications of ulcerative colitis and ulcerative proctitis
268
Clinical features and complications of Crohns disease
291
Mechanisms of systemic inflammation associated with intestinal injury
305
a critical appraisal in diagnosis and management
337
when where and what to
356
Radiologic radiographic and imaging features of ulcerative colitis and Crohns disease
371
New diagnostic approaches in inflammatory bowel disease
426
Disease management in chronic medical conditions
457
Pharmacoeconomics and inflammatory bowel disease
471
Postoperative prevention of recurrence of Crohns disease
697
The molecular pathology of inflammatory bowel diseaseassociated neoplasia and preneoplasia
710
Hepatobiliary disorders
731
Articular and ocular complications of inflammatory bowel disease
746
Fertility and pregnancy in inflammatory bowel disease
763
collagenous and lymphocytic colitis
791
Diversion colitis
811
Infectious colitis
845
Human immunodeficiency virus and inflammatory bowel disease
864
Bone metabolism and inflammatory bowel disease
882
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