Polymer Based Systems on Tissue Engineering, Replacement and RegenerationRui L. Reis, Daniel Cohn Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents. |
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Common terms and phrases
acid acrylic bone cements adhesion apatite applications arterial autologous bioactive biocompatibility biodegradable biodegradable polymers biological Biomater Biomaterials Biomed Biomed Mater Res biomedical biomimetic BMSCs bone cements bone defects bone formation bone marrow bone tissue engineering Ca-P calcium phosphate carbonate cartilage cell seeding ceramics chemical chondrocytes clinical coating collagen composites compression crosslinked culture Cunha degradation differentiation effect endothelial cells extracellular matrix fibroblasts fibrous Figure fracture function growth factors HBMSCs human hydrogels hydroxyapatite immersion implants injection Langer marrow stromal cells materials mechanical properties membranes mesenchymal mesenchymal stem cells methacrylate Mikos mineral modulus molecular weight monomer Orthop orthopaedic osteoblasts PCL scaffolds PMMA polycarbonates polymeric pores porosity porous proliferation prostheses protein Reis release samples scaffolds SEVA-C starch based stem cells stromal cells structure substrates surface surgery technique temperature tensile thermoplastics tissue engineering tissue regeneration transplantation tyrosine-derived polycarbonates Vacanti vascular grafts vitro vivo
References to this book
Nanotechnology for the Regeneration of Hard and Soft Tissues Thomas J. Webster No preview available - 2007 |