Drug Discovery

Front Cover
Hany El-Shemy
BoD – Books on Demand, Jan 23, 2013 - Medical - 526 pages
Natural products are a constant source of potentially active compounds for the treatment of various disorders. The Middle East and tropical regions are believed to have the richest supplies of natural products in the world. Plant derived secondary metabolites have been used by humans to treat acute infections, health disorders and chronic illness for tens of thousands of years. Only during the last 100 years have natural products been largely replaced by synthetic drugs. Estimates of 200 000 natural products in plant species have been revised upward as mass spectrometry techniques have developed. For developing countries the identification and use of endogenous medicinal plants as cures against cancers has become attractive. Books on drug discovery will play vital role in the new era of disease treatment using natural products.
 

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Contents

Anticancer Drug Discovery From Serendipity
35
Drug Interactions Pharmacogenomics and Cardiovascular
75
Interactions with Drugs and Dietary Supplements Used
107
Small Molecule Screens to Identify Inhibitors
157
Practical Considerations of Liquid Handling Devices in Drug
177
Data Analysis Approaches in High Throughput Screening
201
Oxidative Stress in Human Infectious Diseases Present
227
Discovery of Selective and Potent Inhibitors
251
Resources for Drug Discovery
309
Transition State Analogues of Enzymatic Reaction
325
Suppression of ProInflammatory Cytokines via Targeting
373
Coupled Enzyme Activity and Thermal Shift Screening of
413
Current Treatments and Preclinical Models
433
Applications of Snake Venom ProlineRich Oligopeptides Bj
459
Introduction to Biochemical Pharmacology and Drug
475
Copyright

The Antibacterial Drug Discovery
289

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