Inflammatory Bowel DiseaseJoseph B. Kirsner World-renowned experts present state-of-the-art information in the clinical understanding of inflammatory bowel disease in the 5th Edition of this best-selling text. Scholarly and pragmatic, this text features authoritative information on the medical and surgical management of IBD with the support of over 390 illustrations. Features many new chapters, including those covering intestinal permeability in health and disease, the intestinal response to acute inflammation and injuries, and current concepts of IBD etiology and pathogenesis. |
From inside the book
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Page 6
... effects that could be blocked by the presence of anti - IFN - y and anti - tumor necrosis factor - a antibodies . Since recombinant IFN - y and TNF - α have no direct effect on T84 cells , they must exert their effect by stimulation of ...
... effects that could be blocked by the presence of anti - IFN - y and anti - tumor necrosis factor - a antibodies . Since recombinant IFN - y and TNF - α have no direct effect on T84 cells , they must exert their effect by stimulation of ...
Page 103
... effect of smoking is unknown . Cigarette smoking can lead to hyperse- cretion and modification of respiratory mucus by systemic as well as local effects.218 Smoking may have an effect on colonic mucus as well . Colonic mucus in ...
... effect of smoking is unknown . Cigarette smoking can lead to hyperse- cretion and modification of respiratory mucus by systemic as well as local effects.218 Smoking may have an effect on colonic mucus as well . Colonic mucus in ...
Page 338
... effects of medications55 twice that of younger patients.56 Be- cause of this concern , the elderly often are incom- pletely treated.57 Table 22-3 lists the potential side effects of medicines often prescribed in IBD . The many side effects ...
... effects of medications55 twice that of younger patients.56 Be- cause of this concern , the elderly often are incom- pletely treated.57 Table 22-3 lists the potential side effects of medicines often prescribed in IBD . The many side effects ...
Common terms and phrases
acid activity acute addition adhesion agents altered animals antibodies antigen appears associated bacterial barrier cause changes chronic Clin clinical colonic common complex Crohn's disease cytokines defect demonstrated develop effect enhanced enteric epithelial cells epithelium et al evidence experimental expression factor function Gastroenterol Gastroenterology gene genetic growth factor human immune Immunol important incidence increased induced infection inflammation inflammatory bowel disease inhibition initial injury interactions intestinal epithelial cells involved lamina propria levels lymphocytes lymphoid macrophages major mechanisms mediators mice molecules mucosal muscle neutrophils normal observed occurs oral patients permeability Peyer's patches population present produced protective protein rates rats recent receptor region regulation relatives reported response risk role secretion severe showed shown similar small intestine smoking specific stimulation studies suggest surface T-cell Table tion tissue tolerance treatment ulcerative colitis