Inflammatory Bowel DiseaseJoseph B. Kirsner World-renowned experts present state-of-the-art information in the clinical understanding of inflammatory bowel disease in the 5th Edition of this best-selling text. Scholarly and pragmatic, this text features authoritative information on the medical and surgical management of IBD with the support of over 390 illustrations. Features many new chapters, including those covering intestinal permeability in health and disease, the intestinal response to acute inflammation and injuries, and current concepts of IBD etiology and pathogenesis. |
From inside the book
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Page 6
... tion were observed , effects that could be blocked by the presence of anti - IFN - y and anti - tumor necrosis factor - a antibodies . Since recombinant IFN - y and TNF - α have no direct effect on T84 cells , they must exert their ...
... tion were observed , effects that could be blocked by the presence of anti - IFN - y and anti - tumor necrosis factor - a antibodies . Since recombinant IFN - y and TNF - α have no direct effect on T84 cells , they must exert their ...
Page 166
... tion of intestinal inflammation . High luminal concen- trations of FMLP can cause acute colitis250 ; at more physiologic levels , it increases mucosal permeability , particularly in the distal ileum.251 Intravenous injec- tion of LPS ...
... tion of intestinal inflammation . High luminal concen- trations of FMLP can cause acute colitis250 ; at more physiologic levels , it increases mucosal permeability , particularly in the distal ileum.251 Intravenous injec- tion of LPS ...
Page 752
... tion , but the specific transport mechanisms involved are less clearly defined . The colon can increase its ab- sorption of fluid from a normal 1.5 L per day to 4 to 6 L per day . Short - chain fatty acids , as well as mineralo ...
... tion , but the specific transport mechanisms involved are less clearly defined . The colon can increase its ab- sorption of fluid from a normal 1.5 L per day to 4 to 6 L per day . Short - chain fatty acids , as well as mineralo ...
Common terms and phrases
acid activity acute addition adhesion agents altered animals antibodies antigen appears associated bacterial barrier cause changes chronic Clin clinical colonic common complex Crohn's disease cytokines defect demonstrated develop effect enhanced enteric epithelial cells epithelium et al evidence experimental expression factor function Gastroenterol Gastroenterology gene genetic growth factor human immune Immunol important incidence increased induced infection inflammation inflammatory bowel disease inhibition initial injury interactions intestinal epithelial cells involved lamina propria levels lymphocytes lymphoid macrophages major mechanisms mediators mice molecules mucosal muscle neutrophils normal observed occurs oral patients permeability Peyer's patches population present produced protective protein rates rats recent receptor region regulation relatives reported response risk role secretion severe showed shown similar small intestine smoking specific stimulation studies suggest surface T-cell Table tion tissue tolerance treatment ulcerative colitis