Principles of NeurobiologyPrinciples of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors. |
From inside the book
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... increase the intracellular Na+ concentration; however, they are counterbalanced by active transport via the Na+–K+ ATPase, which pumps Na+ out and K+ in (Fig- ure 2-12B). Te Na+–K+ ATPase thus maintains the intracellular K+ and Na+ ...
... increase; similarly more resistance in if parallel, R i is reduced by increasing fber diameter (essentially which decreases the total resistance), then adding more current will strategies fow down to increase R the i , thus increasing λ ...
... increase in membrane permeability to Na+, with the infux of Na+ resulting in further depolarization. Such a self-reinforcing process (positive feedback loop) could account for the rapid change in membrane potential observed during the ...
... increase in Na+ conductance as a consequence of membrane depolarization. Second, after the initial depolarization-induced increase, Na+ conductance would invariably decrease despite continued depolarization (Figure 2-23A), accounting ...
... increase in K+ efux (via resting K+ channels) because the force produced by the new, smaller electrical gradient is ... increase in Na+ conductance, leading to Na+ influx. The falling phase is accounted for by both the inactivation of ...
Contents
1 | |
27 | |
Chapter 3 Signaling across Synapses | 69 |
Chapter 4 Vision | 121 |
Chapter 5 Wiring the Visual System | 173 |
Chapter 6 Olfaction Taste Audition and Somatosensation | 213 |
Chapter 7 Constructing the Nervous System | 281 |
Chapter 8 Motor Systems | 335 |
Chapter 10 Sexual Behavior | 411 |
Chapter 11 Memory Learning and Synaptic Plasticity | 445 |
Chapter 12 Brain Disorders | 499 |
Chapter 13 Evolution of the Nervous System | 547 |
Chapter 14 Ways of Exploring | 591 |
Glossary | 1 |
Index | 1 |
Chapter 9 Regulatory Systems | 375 |