Principles of NeurobiologyPrinciples of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors. |
From inside the book
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... protein names are in roman, and their cases follow the consensus in the literature. Proteins identifed by biochemical means are usually all in lower case; proteins identifed by genetic means or by homology with other genes usually have ...
... protein-induced protein conformational changes 12.9 Aggregation of misfolded proteins is associated with many neurodegenerative diseases 12.10 Parkinson's disease results from death of substantia nigra dopamine neurons 12.11 α-Synuclein ...
... protein (Figure 2-2, left). Genes, the genetic substrates that carry instructions for how and when to make specifc RNAs and proteins, are located in the nucleus on DNA molecules. DNAs are long double-stranded chains of nucleotides ...
... protein products in eukaryotic cells. Proteins localized in the cytosol and nucleus are synthesized on free ribosomes in the cytoplasm, whereas proteins destined for export from the cell (secreted proteins) or that span the lipid ...
... proteins. Proteins from early endosomes can either cycle back to the plasma membrane through exocytosis or be transported to late endosomes and lysosomes, which contain enzymes for protein degradation (Figure 2-2, top right). In Chapter ...
Contents
1 | |
27 | |
Chapter 3 Signaling across Synapses | 69 |
Chapter 4 Vision | 121 |
Chapter 5 Wiring the Visual System | 173 |
Chapter 6 Olfaction Taste Audition and Somatosensation | 213 |
Chapter 7 Constructing the Nervous System | 281 |
Chapter 8 Motor Systems | 335 |
Chapter 10 Sexual Behavior | 411 |
Chapter 11 Memory Learning and Synaptic Plasticity | 445 |
Chapter 12 Brain Disorders | 499 |
Chapter 13 Evolution of the Nervous System | 547 |
Chapter 14 Ways of Exploring | 591 |
Glossary | 1 |
Index | 1 |
Chapter 9 Regulatory Systems | 375 |