Pattern Formation During DevelopmentThe architecture of an embryo results from complex molecular interactions in time and space. The secrets of these processes are yielding quickly to genetic and cellular dissection in flies, mice and other species, and finding application to human embryology. This volume presents a survey of the induction of axes, control of cell migration, and the development of the nervous system, limbs, wings and other organs, seen from the perspective of 61 investigators. It is completed by a summary that charts the future of this dynamic field. |
Contents
| 1 | |
| 13 | |
| 19 | |
| 25 | |
| 35 | |
| 49 | |
| 57 | |
Cortical Asymmetries Direct the Establishment of Cell Polarity and the Plane of Cell Division | 65 |
Control of Cell Growth and Fate by patched Genes R L Johnson and M P Scott | 205 |
Lessons from Bone and Branching Morphogenesis M | 235 |
New Models for a Classical Problem B L M Hogan | 249 |
BMP Signaling and Vertebrate Limb Development H Zou K M Choe Y Lu J Massagué | 270 |
Intercompartmental Signaling and the Regulation of vestigial Expression at the Dorsoventral | 283 |
The Regulation of EnhancerPromoter Interactions in the Drosophila Embryo J Zhou H | 307 |
Role of the Brn3 Family of POUdomain Genes in the Development of the AuditoryVestibu | 325 |
Signaling in Organogenesis | 347 |
Facts and Specula | 71 |
On the Roles of inscuteable in Asymmetric Cell Divisions in Drosophila W Chia R Kraut | 79 |
Maternal Genes with Localized mRNA and Pattern Formation of the Ascidian Embryo | 89 |
Axis Formation | 95 |
Nodal Signaling and Axis Formation in the Mouse I Varlet J Collignon D P Norris | 105 |
Axis Duplication and Anterior Identity in the Mouse Embryo P Thomas J M Brickman | 115 |
FGF Signaling in Mouse Gastrulation and Anteroposterior Patterning J Rossant B Ciruna | 127 |
Lineage and Functional Analyses of the Mouse Organizer P P L Tam K A Steiner S X Zhou | 135 |
Goosecoid and Goosecoidrelated Genes in Mouse Embryogenesis M Wakamiya J Rivera | 145 |
Morphogens | 151 |
Analysis of Fgf8 Gene Function in Vertebrate Development M Lewandowski E N Meyers | 159 |
Brainiac and Fringe Are Similar Pioneer Proteins That Impart Specificity to Notch Signaling | 177 |
Tissue Specification | 191 |
Mutations That Perturb Vulval Invagination in C elegans T Herman and H R Horvitz | 353 |
Control of Cell Division Patterns in Developing Shoots and Flowers of Arabidopsis thaliana | 369 |
The Specification of Muscle in Drosophila M K Baylies M Bate and M Ruiz Gomez | 385 |
A Transcriptional Pathway for Cardiac Development Q Lin D Srivastava and E N Olson | 405 |
Expression of Wnt and Frizzled Genes during Chick Limb Bud Development M Kengaku V | 421 |
Retrovirusmediated Insertional Mutagenesis in Zebrafish and Identification of a Molecular | 437 |
Neural Induction and Pathfinding | 451 |
Guidance of Developing Axons by Netrin1 and Its Receptors E D Leonardo L Hinck M | 467 |
Cell Lineage Determination and the Control of Neuronal Identity in the Neural Crest D J | 493 |
A Reevaluation of Nieuwkoops Twostep Hypothe | 511 |
Cell Interactions in Patterning the Mammalian Midbrain D H Rowitch P S Danielian | 535 |
A Common Language M P Scott | 555 |
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Common terms and phrases
activin activity allele analysis asymmetric axis axons binding Biol Biology bryos cadherins cardiac cell division cell fate chick cholesterol clones Cold Spring Harbor complex defects Dept developmental differentiation domain dorsal Drosophila embryo early ectoderm ectopic elegans embryogenesis embryos enamel knot encodes endoderm expression patterns Fgf8 formation function gastrulation gene expression Genes Dev genetic germ cells germ line growth hindbrain homeobox homolog Hox genes induced insc interactions kinase limb bud lineage localization McMahon mesenchyme mesoderm mice midbrain migration molecular molecules morphogenesis mouse mRNA muscle mutant mutant embryos neural crest neural plate neural tube neurons normal notochord oocyte organizer Pax6 phenotype polarity posterior pression progenitor protein receptor region regulation rhombomere role segment sequence signaling pathway somites Sonic hedgehog specific stage structures suggest synaptic target tion tissues tracheal transcription factor transgenic ventral vertebrate vulval wild-type Xbra Xenopus zebrafish
Popular passages
Page 484 - This work was done during the tenure of an Established Investigatorship from the American Heart Association and with funds contributed in part by the Washington Affiliate.
Page 542 - Chinnaiyan. AM. O'Rourke, K., Tewari, M., and Dixit, VM (1995) FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81, 505-5 12.
Page 501 - C. (1996) Analysis of Hox gene expression in the chick limb bud. Development 122, 1449-1466.
Page 477 - I., and Harvey, RP, 1993, Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants, Development...