The authors have provided a work with their amalgamation of expertise in population genetics, the laws of evidence and molecular biology. 'DNA Profiling' provides a tool in criminal investigatins where by genetic material in tissue residues is analyzed to provide direct identification of an individual. This book serves as a reference source for all aspects of DNA profiling and it clearly describes the underlying principles, as well as the analytical procedures, in language that can be understood by the non-scientist. It considers the scientific aspects and legal implications of obtaining tissue samples and the interpretive problems that can be encountered with the results, with the emphasis on the proper use of evidence based on DNA profiling.
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agarose gel alkali allele frequencies amount of DNA analysis autoradiographs bacterial bands base pairs base sequence blotting buffer cells centrifuge chromosome coincidental matching containing Court crime scene Crimes Act 1900 Criminal denatured detainee detected digestion discretion DNA duplex DNA fragments DNA probes DNA profiling DNA sequence dot blot electrophoresis estimate ethanol ethidium bromide examination expert Figure Forensic Science four bases fragment length fragment sizes gene genetic genome genotypes Hardy-Weinberg Hardy-Weinberg law human hybridization solution identification individual jury labeled probe laboratory Lifecodes linkage disequilibrium markers measurement migration molecular multilocus nitrocellulose nylon membrane obtained particular plasmid police population frequencies probe DNA procedures refer to Chapter repeated residue restriction digestion restriction enzyme restriction fragments RFLP scientific separated sequence of bases specific specimen sperm stained standard strands suspect target DNA target sequence techniques temperature test gel tissue transfer tube usually variation VNTR loci VNTR probes X-ray film