Hippocampal Place Fields: Relevance to Learning and MemorySheri J.Y. Mizumori Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function. |
From inside the book
Results 1-5 of 84
Page xix
... maze . The maternal chamber was a large box with clear walls , also placed on the radial - arm maze . We saw spatial correlates as described by O'Keefe in virtually every complex - spike cell that was well isolated . An indi- vidual ...
... maze . The maternal chamber was a large box with clear walls , also placed on the radial - arm maze . We saw spatial correlates as described by O'Keefe in virtually every complex - spike cell that was well isolated . An indi- vidual ...
Page 9
... maze learning and fear conditioning , respectively , back to a fragile state , and that these newly fragile memories could be disrupted by the systemic injection of MK - 801 ( an NMDA receptor antagonist ) or protein synthesis ...
... maze learning and fear conditioning , respectively , back to a fragile state , and that these newly fragile memories could be disrupted by the systemic injection of MK - 801 ( an NMDA receptor antagonist ) or protein synthesis ...
Page 17
... maze. Es- chenko and Mizumori (2007) showed an explicit in- fluence of cognitive/memory demand that was inde- pendent of behavioral trajectories. They showed that place fields are also guided by the cognitive strategy (e.g., spatial or ...
... maze. Es- chenko and Mizumori (2007) showed an explicit in- fluence of cognitive/memory demand that was inde- pendent of behavioral trajectories. They showed that place fields are also guided by the cognitive strategy (e.g., spatial or ...
Page 21
... maze. According to the CDH, the combined activity pro- files of hippocampal pyramidal cells (and interneu- rons) represent an experience-dependent context code that is unique for a particular test situation. Individual place fields have ...
... maze. According to the CDH, the combined activity pro- files of hippocampal pyramidal cells (and interneu- rons) represent an experience-dependent context code that is unique for a particular test situation. Individual place fields have ...
Page 25
... maze regardless of the start location. These cells were considered to rep- resent prospective information about the ... mazes (e.g., Gothard et al., 1996; Ferbinteanu and Shapiro, 2003). In summary, these findings are consistent with the ...
... maze regardless of the start location. These cells were considered to rep- resent prospective information about the ... mazes (e.g., Gothard et al., 1996; Ferbinteanu and Shapiro, 2003). In summary, these findings are consistent with the ...
Contents
II Primate Hippocampus and Place Representation | 175 |
III Neural Systems Perspective on the Significance of Place Fields | 235 |
IV Theoretical Significance of Place Fields | 311 |
V Place Fields and AgeRelated Changes in Memory | 351 |
Author Index | 385 |
Subject Index | 397 |
Other editions - View all
Hippocampal Place Fields:Relevance to Learning and Memory: Relevance to ... Sheri J.Y. Mizumori No preview available - 2008 |
Common terms and phrases
amygdala animal arena associated Barnes Behav Neurosci behavioral Brain Res campal changes coding cognitive map correlates cortical cues dentate gyrus dopamine dorsal Eichenbaum encoding ensemble entorhinal cortex environment episodic memory firing fields firing patterns firing rate function Fyhn goal grid cells Hasselmo head direction cells hippo hippocampal activity hippocampal cells hippocampal formation hippocampal neurons hippocampal place cells hippocampal subfields idiothetic impaired input Kesner Kubie learning lesions Leutgeb maze McNaughton BL medial memory tasks Mizumori modulation monkey Muller RU Nadel navigation neural Neurobiol neuronal activity Neurosci NMDA nonspatial O'Keefe path integration performance perirhinal perirhinal cortex phase place cell activity place cell firing place fields plasticity pocampal prefrontal cortex processing receptor remapping responses retrieval reward role Rolls sensory signal space spatial firing spatial memory spatial representations spatial view spike stimuli studies subiculum synaptic temporal theta rhythm tion Treves trials visual