Biology, Toxicology and Carcinogenesis of Respiratory EpitheliumG. Thomassen This broadly-based reference resource was compiled as a result of the rapid rise in lung cancer incidence among the world's industrialized nations. Leading researchers address modern research on the respiratory epithelium. |
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Page vii
... Autocrine Growth Factors That Regulate the Proliferation of Pulmonary Malignancies in Man F. Cuttitta , P. G. Kasprzyk , A. M. Treston , I. Avis , S. Jensen , M. Levitt , J. Siegfried , C. Modley , and J. L. Mulshine Activated Oncogenes ...
... Autocrine Growth Factors That Regulate the Proliferation of Pulmonary Malignancies in Man F. Cuttitta , P. G. Kasprzyk , A. M. Treston , I. Avis , S. Jensen , M. Levitt , J. Siegfried , C. Modley , and J. L. Mulshine Activated Oncogenes ...
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Contents
Biology of Respiratory Epithelium | xiii |
Composition Differentiation and Response to Hormones | 4 |
In Vivo Composition Differentiation and Response to Hormones | 22 |
The Functions of Pulmonary Clara Cells | 36 |
Growth and Differentiation of Pulmonary Alveolar Epithelial Cells | 58 |
Markers for Differentiated Alveolar Cells | 65 |
Identification of Multiple Stages in the Program of Squamous Differentiation in Tracheobronchial | 72 |
Epithelial Progenitor Cells in the Rat Respiratory Tract | 86 |
Respiratory Epithelial Injury and Repair | 153 |
Inhaled Diesel Exhaust Induces DNA Adducts in the Rat Respiratory Tract | 170 |
Cell Specificity for DNA Methylation and Repair in Rat Lung Following Exposure to Nitrosamines | 180 |
Carcinogenesis of Respiratory Epithelium | 191 |
Mechanisms of Neuroendocrine Lung Carcinogenesis | 193 |
Changes in Cellular Responses to Inducers of Differentiation Growth Factors and Oncogenes During Neoplastic Progression of Respiratory Epithelial ... | 203 |
Growth Differentiation and Transformation Studies of Human Bronchial Epithelial Cells | 215 |
226 | |
The Role of Clara Cells and Basal Cells as Epithelial Stem Cells of the Conducting Airways | 97 |
In Vitro Studies of Human Mesothelioma | 110 |
Toxicology of Respiratory Epithelium | 123 |
Responses of Type II Pneumocytes to Oxidant Stress | 127 |
Involvement of Active Oxygen Species AOS in Injury Repair and Proliferation of Tracheobronchial Epithelial Cells After Exposure to Asbestos Fibers | 143 |
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acid adenocarcinomas airway alveolar alveolar type antibody asbestos autocrine basal cells binding Biochem Biol bombesin bronchial epithelial cells bronchiolar Cancer Res carcinogenesis carcinogenic carcinoma cell lung cancer cell proliferation cell types cellular chemical ciliated ciliated cells Clara cells codon cultures DNA adducts enzyme epithelial cells exposure fetal formaldehyde function Gazdar granules hamster hormone human lung IGF-I induced isolated Jetten K-ras K-ras gene lamellar bodies lesions levels lung cancer lung cancer cells lung tumors medium mesothelial mesothelial cells mesothelioma metabolism mice molecular mouse mRNA mucous mutations nasal Natl NDMA neoplastic Nettesheim neuroendocrine NHBE nitrosamines normal oncogenes oxidant oxygen pathway peptide Plopper PNE cells preneoplastic protein pulmonary rabbit rat lung receptor respiratory epithelium response RTE cells secretory cells small cell lung species squamous differentiation studies surface surfactant tion tissue toxicity tracheal epithelium tracheobronchial epithelium transformation tumor cell type II cells ultrastructural uteroglobin vitro vivo xanthine xanthine oxidase