Biology, Toxicology and Carcinogenesis of Respiratory Epithelium

Front Cover
G. Thomassen
CRC Press, Dec 1, 1989 - Medical

This broadly-based reference resource was compiled as a result of the rapid rise in lung cancer incidence among the world's industrialized nations. Leading researchers address modern research on the respiratory epithelium.

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Contents

Biology of Respiratory Epithelium
xiii
Composition Differentiation and Response to Hormones
4
In Vivo Composition Differentiation and Response to Hormones
22
The Functions of Pulmonary Clara Cells
36
Growth and Differentiation of Pulmonary Alveolar Epithelial Cells
58
Markers for Differentiated Alveolar Cells
65
Identification of Multiple Stages in the Program of Squamous Differentiation in Tracheobronchial
72
Epithelial Progenitor Cells in the Rat Respiratory Tract
86
Respiratory Epithelial Injury and Repair
153
Inhaled Diesel Exhaust Induces DNA Adducts in the Rat Respiratory Tract
170
Cell Specificity for DNA Methylation and Repair in Rat Lung Following Exposure to Nitrosamines
180
Carcinogenesis of Respiratory Epithelium
191
Mechanisms of Neuroendocrine Lung Carcinogenesis
193
Changes in Cellular Responses to Inducers of Differentiation Growth Factors and Oncogenes During Neoplastic Progression of Respiratory Epithelial ...
203
Growth Differentiation and Transformation Studies of Human Bronchial Epithelial Cells
215
Autocrine Growth Factors That Regulate the Proliferation of Pulmonary Malignancies in Man
226

The Role of Clara Cells and Basal Cells as Epithelial Stem Cells of the Conducting Airways
97
In Vitro Studies of Human Mesothelioma
110
Toxicology of Respiratory Epithelium
123
Responses of Type II Pneumocytes to Oxidant Stress
127
Involvement of Active Oxygen Species AOS in Injury Repair and Proliferation of Tracheobronchial Epithelial Cells After Exposure to Asbestos Fibers
143
Activated Oncogenes in Rodent and Human Lung Tumors
269
Dominant and Recessive Oncogenes in the Pathogenesis of Lung Cancer
286
Index
304
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