Enteroimmunology: A Guide to the Prevention and Treatment of Chronic Inflammatory Disease

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Psy Press, Jan 18, 2017 - Medical - 550 pages

Enteroimmunology is the emerging field of medicine that studies the enteric immune system and microbial biome of the digestive system, and their interaction with diet, digestion, the enteric and central nervous systems and endocrine functions. It explores and elucidates how these systems affect each other, impacting health and disease. Enteroimmune disease is not limited to diseases such as irritable bowel syndrome and inflammatory bowel diseases but also cause systemic and neurological diseases. Neurological diseases discussed include autism, migraine, chronic fatigue syndrome, multiple sclerosis, bipolar and rage disorders. The gastrointestinal mucosa is predominantly lined with enterocytes that form a continuous barrier throughout the digestive path. These cells absorb nutrients while excluding the trillions of bacteria and other microbes that inhabit the gut. Just below the enterocytes, the mucosa contains over half of the body’s immune cells. These cells effect immune activity that protect the body from infection. However, they can also promote chronic inflammation, not just in the intestines, but in any organ system of the body. This book details the physiologic functions of the digestive and immune cells; their reactions to proteins, antigens and nutrients in the diet; the role of bacterial toxins and immune mediators; and the hormones that mediate appetite, GI motility and digestion. It explores the mechanisms occurring in immune dysfunction; when the immune response, rather than protect health, promotes chronic inflammation, responsible for depression, obesity, diabetes, acne, Alzheimer’s disease, cancer, migraines, fibromyalgia, IBS, osteoporosis, schizophrenia, and many other chronic inflammatory diseases. Understanding the immune system of the gut, provides insight to how these mechanisms impact both the enteric and central nervous systems. Dr. Lewis elucidates the physiology and pathophysiology of the intestinal and immune cells with clarity and humor that makes reading this book a pleasure. Enteroimmunology describes how various types of food sensitivities, including IgG antergies, which are analogous to IgE allergies, cause a wide array of chronic disease. This book explains mast cell activation syndrome, leaky gut syndrome, small bowel overgrowth, dysbiosis, metabolic syndrome and describes how to achieve long-term effective resolution of these conditions through diet. The book provides examples of a variety of conditions and the pathological processes that underlie them and then acts a guide to the tertiary treatment for the condition. There are chapters on obesity and metabolic syndrome, mood and thought disorders, fibromyalgia, autoimmune diseases, interstitial cystitis, sexual dysfunction, acne and other diseases. A chapter is dedicated to traumatic brain injury and its secondary prevention. Another chapter focuses on cancer prevention and explains the dietary factors responsible for the majority of human cancers, and provides practical, evidenced-based advice for cancer prevention. There is a chapter explaining how the mitochondria and aging, detailing of how individuals can maintain vibrant, healthy, mitochondria. There are chapters on the role of sleep disorders in enteroimmune disease, explaining the role osteoimmunity in osteoporosis and on prevention of hearing loss. Enteroimmunology is a guide to the prevention and the reversal of chronic disease by first understanding, and then using diet and nutrition to reverse the underlying causation of these diseases. Enteroimmunology explains the emerging understanding of the ecology of the gut and its relationship with diet, food and nutrition. This highly acclaimed book, now in its 3rd edition, has been extensively updated and expanded. It provides citations to National Library of Medicine PMID numbers that link to over a thousand free, full-length scientific

 

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Contents

30 Traumatic Brain Injury 2018
292
31 Depression 2018
322
32 Fibromyalgia 2018
351
33 TH17 Autoimmune disorders 2018
370
34 IBD 2018
376
35 Autism 2018
387
36 Rage 2018
397
37 Acne 2018
406

09 Syndrome X 2018
80
10 Immune cells 2018
93
11 IgE Food Allergies 2018
107
12 Mast Cell Activation Disorder 2018
116
13 Bioamine Pseudoallergy 2018
125
14 Degranulation 2018
142
15 Leukotriene IH 2018
148
16 Enzyme Reactions 2018
159
17 The Dark side of Dark Chocolate and Wine 2018
161
18 Immune Hypersensitivity 2018
168
19 Food Hypersensitivity 2018
172
20 Vitamin D3 2018
183
21 Mitochondria and Disease and Aging 2018
192
22 Gluten Disease 2018
208
23 Biofilms 2018
218
24 SIBO 2018
231
25 Leaky Gut Syndrome 2018
243
26 Irritable Bowel Syndrome 2018
254
27 Interstitial Cystitis 2015
263
28 Headaches 2018
267
29 HPA Axis and Stress 2018
278
38 Sexual Dysfunction 2018
419
39 Food Additives 2018
423
40 Supplements 2018
427
41 Cancer Prevention 2018
448
42 Osteoimmunity 2018
476
43 Sleep 2018
487
44 Hearing and Balance 2018
506
45 Public Health Measures 2018
515
Appendix A Cross Reactivity 2018
520
APPENDIX B 2018
523
Appendix C Lab tests 2018
524
Appendix D DV questionnaire 2018
525
Appendix E Exercise questionnaire 2018
527
Appendix F Urgency 2018
528
APPENDIX G PTSD 2018
529
Appendix H Methionine Restriction 2018
530
Appendix I Desensization 2018
533
Appendix J TPI 2018
534
Appendix K Adjusting Car Seats 2018
536
Az Index 2018
539
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