Beyond the Cognitive Map: From Place Cells to Episodic Memory
MIT Press, 1999 - Medical - 420 pages
There are currently two major theories about the role of the hippocampus, a distinctive structure in the back of the temporal lobe. One says that it stores a cognitive map, the other that it is a key locus for the temporary storage of episodic memories. A. David Redish takes the approach that understanding the role of the hippocampus in space will make it possible to address its role in less easily quantifiable areas such as memory. Basing his investigation on the study of rodent navigation--one of the primary domains for understanding information processing in the brain--he places the hippocampus in its anatomical context as part of a greater functional system.
Redish draws on the extensive experimental and theoretical work of the last 100 years to paint a coherent picture of rodent navigation. His presentation encompasses multiple levels of analysis, from single-unit recording results to behavioral tasks to computational modeling. From this foundation, he proposes a novel understanding of the role of the hippocampus in rodents that can shed light on the role of the hippocampus in primates, explaining data from primate studies and human neurology. The book will be of interest not only to neuroscientists and psychologists, but also to researchers in computer science, robotics, artificial intelligence, and artificial life.
Results 1-5 of 5
Cells with firing rates reflecting head direction have been discovered in a number
of structures in the rodent brain: post- subiculum (NS; Ranck, 1984; Taube, Muller
, and Ranck, 1990a, 1990b), the anterior thalamic nuclei (ATN; Blair and Sharp ...
Some cells showed bimodal head direction tuning curves during cue
manipulation trials (Chen, 1991; Chen et al., 1994b), something never seen in
anterior thalamic or postsubicular recordings. Lateral dorsal thalamus and
parietal cortex may ...
Unfortunately, postsubiculum lesions do not seem to disrupt the directional
selectivity of anterior thalamic cells (Goodridge and Taube, 1994; Taube et al.,
1996). This result is incompatible with the attractor network model. There are
This means that it can be learned once early in life, or even prewired genetically.
However, the subiculum does not send output directly to the place code; it sends
output to the postsubiculum, to the para- subiculum, to layer IV of the entorhinal ...
Lesions of the rat postsubiculum impair performance on spatial tasks. Behavioral
and Neural Biology 5: 131-143. Taube, J. S., R. I. Muller, and J. B. Ranck, Jr. (
1990a). Head direction cells recorded from the postsubiculum in freely moving