High-dose Cancer Therapy: Pharmacology, Hematopoietins, Stem Cells, Volume 638James O. Armitage, Karen Antman The third edition of this comprehensive reference on high dose cancer therapy has been overhauled, with 28 of 50 chapters either completely updated or rewritten by new authors. This is designed to reflect the fact that this treatment modality is now the standard of care for a variety of cancers, including 10,000 to 20,000 cases a year of various forms of leukaemia, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma, lung cancer, ovarian cancer, and more. High dosage chemotherapy is now also used in advanced cases of breast cancer. |
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Contents
Pharmacologic Strategies for HighDose Therapy | 3 |
Preclinical Models for HighDose Therapy | 15 |
Pharmacokinetics | 49 |
Copyright | |
46 other sections not shown
Common terms and phrases
activity acute addition agents allogeneic amphotericin analysis antibody antigen associated autologous bone marrow body bone marrow transplantation breast cancer catheters cause Center chemotherapy chronic Clin Oncol clinical colony-stimulating factor combination compared complications costs culture cyclophosphamide decreased detection disease donor dose drug early effects Engl engraftment et al evaluation factor fraction function gene given GM-CSF graft granulocyte growth GVHD hematopoietic high-dose human ifosfamide immune important incidence increased infection infusion irradiation less leukemia levels long-term lymphoma malignancies mobilization months normal occur Oncology outcome patients peripheral blood phase plantation platelet potential prevention production progenitor cells purging radiation randomized receiving recipients recombinant recovery regimens relapse reported response risk selection sensitivity showed significant single stem cell techniques therapy tients tion toxicity trans transfusion treated treatment trial tumor cells unrelated versus vitro vivo
References to this book
Blood Stem Cell Transplantation Josy Reiffers,John M Goldman,James O Armitage No preview available - 1998 |